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HOW ACCURATELY CAN A SINGLE MOLECULE BE LOCALIZED WHEN IMAGED THROUGH AN OPTICAL MICROSCOPE?
We present a simple analytical expression for the fundamental limit to the accuracy with which the location of a single molecule can be determined that is imaged through an optical microscope. This expression depends on the optical properties of the microscope and the photophysical properties of the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800313/ https://ncbi.nlm.nih.gov/pubmed/20046822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/ISBI.2004.1398731 |
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