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Localization Accuracy in Single-Molecule Microscopy

One of the most basic questions in single-molecule microscopy concerns the accuracy with which the location of a single molecule can be determined. Using the Fisher information matrix it is shown that the limit of the localization accuracy for a single molecule is given by [Formula: see text] , wher...

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Hlavní autoři: Ober, Raimund J., Ram, Sripad, Ward, E. Sally
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303911/
https://ncbi.nlm.nih.gov/pubmed/14747353
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