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Investigation of the numerics of point spread function integration in single molecule localization

The computation of point spread functions, which are typically used to model the image profile of a single molecule, represents a central task in the analysis of single molecule microscopy data. To determine how the accuracy of the computation affects how well a single molecule can be localized, we...

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Detalhes bibliográficos
Publicado no:Opt Express
Main Authors: Chao, Jerry, Ram, Sripad, Lee, Taiyoon, Ward, E. Sally, Ober, Raimund J.
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523554/
https://ncbi.nlm.nih.gov/pubmed/26191698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/OE.23.016866
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