Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88

Heparan sulfates (HS) bind a diversity of protein ligands on the cell surface and in the extracellular matrix and thus can modulate cell signaling. The state of sulfation in glucosamines and uronic acids within the chains strongly influences their binding. We have previously cloned and characterized...

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Autores principales: Hossain, Md Motarab, Hosono-Fukao, Tomomi, Tang, Renhong, Sugaya, Noriko, van Kuppevelt, Toin H, Jenniskens, Guido J, Kimata, Koji, Rosen, Steven D, Uchimura, Kenji
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800247/
https://ncbi.nlm.nih.gov/pubmed/19822709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp159
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