Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88

Heparan sulfates (HS) bind a diversity of protein ligands on the cell surface and in the extracellular matrix and thus can modulate cell signaling. The state of sulfation in glucosamines and uronic acids within the chains strongly influences their binding. We have previously cloned and characterized...

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Main Authors: Hossain, Md Motarab, Hosono-Fukao, Tomomi, Tang, Renhong, Sugaya, Noriko, van Kuppevelt, Toin H, Jenniskens, Guido J, Kimata, Koji, Rosen, Steven D, Uchimura, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800247/
https://ncbi.nlm.nih.gov/pubmed/19822709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp159
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