Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88

Heparan sulfates (HS) bind a diversity of protein ligands on the cell surface and in the extracellular matrix and thus can modulate cell signaling. The state of sulfation in glucosamines and uronic acids within the chains strongly influences their binding. We have previously cloned and characterized...

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Bibliographic Details
Main Authors: Hossain, Md Motarab, Hosono-Fukao, Tomomi, Tang, Renhong, Sugaya, Noriko, van Kuppevelt, Toin H, Jenniskens, Guido J, Kimata, Koji, Rosen, Steven D, Uchimura, Kenji
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800247/
https://ncbi.nlm.nih.gov/pubmed/19822709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp159
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