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Statistical tests for natural selection on regulatory regions based on the strength of transcription factor binding sites

BACKGROUND: Although cis-regulatory changes play an important role in evolution, it remains difficult to establish the contribution of natural selection to regulatory differences between species. For protein coding regions, powerful tests of natural selection have been developed based on comparisons...

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Autore principale: Moses, Alan M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800119/
https://ncbi.nlm.nih.gov/pubmed/19995462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-9-286
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