Genetic Variants in Transcription Factor Binding Sites in Humans: Triggered by Natural Selection and Triggers of Diseases

Variants of transcription factor binding sites (TFBSs) constitute an important part of the human genome. Current evidence demonstrates close links between nucleotides within TFBSs and gene expression. There are multiple pathways through which genomic sequences located in TFBSs regulate gene expressi...

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Publicat a:Int J Mol Sci
Autors principals: Tseng, Chia-Chun, Wong, Man-Chun, Liao, Wei-Ting, Chen, Chung-Jen, Lee, Su-Chen, Yen, Jeng-Hsien, Chang, Shun-Jen
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073710/
https://ncbi.nlm.nih.gov/pubmed/33919522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084187
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