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Genetic Variants in Transcription Factor Binding Sites in Humans: Triggered by Natural Selection and Triggers of Diseases

Variants of transcription factor binding sites (TFBSs) constitute an important part of the human genome. Current evidence demonstrates close links between nucleotides within TFBSs and gene expression. There are multiple pathways through which genomic sequences located in TFBSs regulate gene expressi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Tseng, Chia-Chun, Wong, Man-Chun, Liao, Wei-Ting, Chen, Chung-Jen, Lee, Su-Chen, Yen, Jeng-Hsien, Chang, Shun-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073710/
https://ncbi.nlm.nih.gov/pubmed/33919522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084187
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