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Genome-wide inference of natural selection on human transcription factor binding sites
For decades, it has been hypothesized that gene regulation has had central role in human evolution, yet much remains unknown about the genome-wide impact of regulatory mutations. Here we use whole-genome sequences and genome-wide chromatin immunoprecipitation and sequencing data to demonstrate that...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932982/ https://ncbi.nlm.nih.gov/pubmed/23749186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2658 |
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