Genetic dissection of the miR-17∼92 cluster of microRNAs in Myc-induced B-cell lymphomas

The miR-17∼92 cluster is frequently amplified or overexpressed in human cancers and has emerged as the prototypical oncogenic polycistron microRNA (miRNA). miR-17∼92 is a direct transcriptional target of c-Myc, and experiments in a mouse model of B-cell lymphomas have shown cooperation between these...

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Bibliografiske detaljer
Main Authors: Mu, Ping, Han, Yoon-Chi, Betel, Doron, Yao, Evelyn, Squatrito, Massimo, Ogrodowski, Paul, de Stanchina, Elisa, D'Andrea, Aleco, Sander, Chris, Ventura, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2009
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800095/
https://ncbi.nlm.nih.gov/pubmed/20008931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1872909
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