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Adaptive response by state-dependent inactivation

Many membrane channels and receptors exhibit adaptive, or desensitized, response to a strong sustained input stimulus. A key mechanism that underlies this response is the slow, activity-dependent removal of responding molecules to a pool which is unavailable to respond immediately to the input. This...

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Bibliografiske detaljer
Main Authors: Friedlander, Tamar, Brenner, Naama
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799740/
https://ncbi.nlm.nih.gov/pubmed/20018770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902146106
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