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Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro.
We have found that purified calf thymus DNA topoisomerase II mediates recombination between two phage lambda DNA molecules in an in vitro system. The enzyme mainly produced a linear monomer recombinant DNA that can be packaged in vitro. Novobiocin and anti-calf thymus DNA topoisomerase II antibody i...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1988
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2832845/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.7.2076 |
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