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Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro.

We have found that purified calf thymus DNA topoisomerase II mediates recombination between two phage lambda DNA molecules in an in vitro system. The enzyme mainly produced a linear monomer recombinant DNA that can be packaged in vitro. Novobiocin and anti-calf thymus DNA topoisomerase II antibody i...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bae, Y S, Kawasaki, I, Ikeda, H, Liu, L F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279931/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2832845/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.7.2076
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