Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV purified from Staphylococcus aureus.

In order to clarify the mechanism of action of quinolones against Staphylococcus aureus, GrlA and GrlB proteins of topoisomerase IV encoded by genes with or without mutations were purified separately as fusion proteins with maltose-binding protein in Escherichia coli. The reconstituted enzymes showe...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Tanaka, M, Onodera, Y, Uchida, Y, Sato, K, Hayakawa, I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2362
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