NAD(P)H Oxidase Mediates TGF-β1–Induced Activation of Kidney Myofibroblasts

TGF-β1 expression closely associates with activation and conversion of fibroblasts to a myofibroblast phenotype and synthesis of an alternatively spliced cellular fibronectin variant, Fn-ED-A. Reactive oxygen species (ROS), such as superoxide, which is a product of NAD(P)H oxidase, also promote the...

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Main Authors: Bondi, Corry D., Manickam, Nagaraj, Lee, Duck Yoon, Block, Karen, Gorin, Yves, Abboud, Hanna E., Barnes, Jeffrey L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2010
Ábhair:
Basic Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799274/
https://ncbi.nlm.nih.gov/pubmed/19926889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009020146
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