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RhoA/Rho kinase mediates TGF-β(1)-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species
The small G proteins Rac1 and RhoA regulate actin cytoskeleton, cell shape, adhesion, migration, and proliferation. Recent studies in our laboratory have shown that NADPH oxidase Nox4-derived ROS are involved in transforming growth factor (TGF)-β(1)-induced rat kidney myofibroblast differentiation a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101629/ https://ncbi.nlm.nih.gov/pubmed/24872317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00546.2013 |
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