Non-cell-autonomous retinoid signaling is crucial for renal development

In humans and mice, mutations in the Ret gene result in Hirschsprung's disease and renal defects. In the embryonic kidney, binding of Ret to its ligand, Gdnf, induces a program of epithelial cell remodeling that controls primary branch formation and branching morphogenesis within the kidney. Ou...

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Dettagli Bibliografici
Autori principali: Rosselot, Carolina, Spraggon, Lee, Chia, Ian, Batourina, Ekatherina, Riccio, Paul, Lu, Benson, Niederreither, Karen, Dolle, Pascal, Duester, Gregg, Chambon, Pierre, Costantini, Frank, Gilbert, Thierry, Molotkov, Andrei, Mendelsohn, Cathy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2010
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799161/
https://ncbi.nlm.nih.gov/pubmed/20040494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.040287
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