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Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation

Vitamin A homoeostasis requires the gene encoding cellular retinol-binding protein-1 (Crbp1) which stimulates conversion of retinol into retinyl esters that serve as a storage form of vitamin A. The gene encoding alcohol dehydrogenase-1 (Adh1) greatly facilitates degradative metabolism of excess ret...

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Détails bibliographiques
Auteurs principaux: Molotkov, Andrei, Ghyselinck, Norbert B., Chambon, Pierre, Duester, Gregg
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134070/
https://ncbi.nlm.nih.gov/pubmed/15193143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040621
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