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Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning

Retinoic acid (RA) is required for patterning of the posterior nervous system, but its role in the retina remains unclear. RA is synthesized in discrete regions of the embryonic eye by three retinaldehyde dehydrogenases (RALDHs) displaying distinct expression patterns. Overlapping functions of these...

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Bibliografiske detaljer
Main Authors: Molotkov, Andrei, Molotkova, Natalia, Duester, Gregg
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833011/
https://ncbi.nlm.nih.gov/pubmed/16611695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02328
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