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Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning

Retinoic acid (RA) is required for patterning of the posterior nervous system, but its role in the retina remains unclear. RA is synthesized in discrete regions of the embryonic eye by three retinaldehyde dehydrogenases (RALDHs) displaying distinct expression patterns. Overlapping functions of these...

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Détails bibliographiques
Auteurs principaux: Molotkov, Andrei, Molotkova, Natalia, Duester, Gregg
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833011/
https://ncbi.nlm.nih.gov/pubmed/16611695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02328
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