Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3

Influence of vitamin A (retinol) on growth depends on its sequential oxidation to retinal and then to retinoic acid (RA), producing a ligand for RA receptors essential in development of specific tissues. Genetic studies have revealed that aldehyde dehydrogenases function as tissue-specific catalysts...

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Autors principals: Molotkov, Andrei, Fan, Xiaohong, Deltour, Louise, Foglio, Mario H., Martras, Sílvia, Farrés, Jaume, Parés, Xavier, Duester, Gregg
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC122770/
https://ncbi.nlm.nih.gov/pubmed/11959987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082093299
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