Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3

Influence of vitamin A (retinol) on growth depends on its sequential oxidation to retinal and then to retinoic acid (RA), producing a ligand for RA receptors essential in development of specific tissues. Genetic studies have revealed that aldehyde dehydrogenases function as tissue-specific catalysts...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Molotkov, Andrei, Fan, Xiaohong, Deltour, Louise, Foglio, Mario H., Martras, Sílvia, Farrés, Jaume, Parés, Xavier, Duester, Gregg
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122770/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082093299
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