Non-cell-autonomous retinoid signaling is crucial for renal development

In humans and mice, mutations in the Ret gene result in Hirschsprung's disease and renal defects. In the embryonic kidney, binding of Ret to its ligand, Gdnf, induces a program of epithelial cell remodeling that controls primary branch formation and branching morphogenesis within the kidney. Ou...

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Detalhes bibliográficos
Main Authors: Rosselot, Carolina, Spraggon, Lee, Chia, Ian, Batourina, Ekatherina, Riccio, Paul, Lu, Benson, Niederreither, Karen, Dolle, Pascal, Duester, Gregg, Chambon, Pierre, Costantini, Frank, Gilbert, Thierry, Molotkov, Andrei, Mendelsohn, Cathy
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799161/
https://ncbi.nlm.nih.gov/pubmed/20040494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.040287
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