Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure

We performed experiments to characterize the inducibility of nucleotide excision repair (NER) in Caenorhabditis elegans, and to examine global gene expression in NER-deficient and -proficient strains as well as germline vs. somatic tissues, with and without genotoxic stress. We also carried out expe...

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Autori principali: Boyd, Windy A., Crocker, Tracey L., Rodriguez, Ana M., Leung, Maxwell C. K., Lehmann, D. Wade, Freedman, Jonathan H., Van Houten, Ben, Meyer, Joel N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799044/
https://ncbi.nlm.nih.gov/pubmed/19879883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.10.008
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