Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans

BACKGROUND: Caenorhabditis elegans is an important model for the study of DNA damage and repair related processes such as aging, neurodegeneration, and carcinogenesis. However, DNA repair is poorly characterized in this organism. We adapted a quantitative polymerase chain reaction assay to character...

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Bibliographic Details
Main Authors: Meyer, Joel N, Boyd, Windy A, Azzam, Gregory A, Haugen, Astrid C, Freedman, Jonathan H, Van Houten, Bennett
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929140/
https://ncbi.nlm.nih.gov/pubmed/17472752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-5-r70
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