Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β

The base excision DNA repair (BER) pathway known to occur in Caenorhabditis elegans has not been well characterized. Even less is known about the DNA polymerase (pol) requirement for the gap-filling step during BER. We now report on characterization of in vitro uracil-DNA initiated BER in C. elegans...

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Detalhes bibliográficos
Main Authors: Asagoshi, Kenjiro, Lehmann, Wade, Braithwaite, Elena K., Santana-Santos, Lucas, Prasad, Rajendra, Freedman, Jonathan H., Van Houten, Bennett, Wilson, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258131/
https://ncbi.nlm.nih.gov/pubmed/21917855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr727
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