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Caenorhabditis elegans Generates Biologically Relevant Levels of Genotoxic Metabolites from Aflatoxin B(1) but Not Benzo[a]pyrene In Vivo

There is relatively little information regarding the critical xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in Caenorhabditis elegans, despite this organism's increasing use as a model in toxicology and pharmacology. We carried out experiments to elucidate the capacity of C. elegans to...

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Detalhes bibliográficos
Main Authors: Leung, Maxwell C. K., Goldstone, Jared V., Boyd, Windy A., Freedman, Jonathan H., Meyer, Joel N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984530/
https://ncbi.nlm.nih.gov/pubmed/20864627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq295
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