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Perylenequinone Natural Products: Total Syntheses of the Diastereomers (+)-Phleichrome and (+)-Calphostin D by Assembly of Centrochiral and Axial Chiral Fragments

[Image: see text] The first total synthesis of (+)-calphostin D and the total synthesis of (+)-phleichrome are outlined. The convergent syntheses utilize an enantiopure biaryl common intermediate, which is formed via an enantioselective catalytic biaryl coupling. The established axial chirality is t...

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Detalhes bibliográficos
Main Authors: Morgan, Barbara J., Mulrooney, Carol A., O’Brien, Erin M., Kozlowski, Marisa C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798900/
https://ncbi.nlm.nih.gov/pubmed/19894745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo901384h
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