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Model of human low-density lipoprotein and bound receptor based on CryoEM
Human plasma low-density lipoproteins (LDL), a risk factor for cardiovascular disease, transfer cholesterol from plasma to liver cells via the LDL receptor (LDLr). Here, we report the structures of LDL and its complex with the LDL receptor extracellular domain (LDL·LDLr) at extracellular pH determin...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798884/ https://ncbi.nlm.nih.gov/pubmed/20080547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908004107 |
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