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Interprotofilament interactions between Alzheimer's Aβ(1–42) peptides in amyloid fibrils revealed by cryoEM
Alzheimer's disease is a neurodegenerative disorder characterized by the accumulation of amyloid plaques in the brain. This amyloid primarily contains amyloid-β (Aβ), a 39- to 43-aa peptide derived from the proteolytic cleavage of the endogenous amyloid precursor protein. The 42-residue-length...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660777/ https://ncbi.nlm.nih.gov/pubmed/19264960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901085106 |
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