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Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR)
The constitutive androstane receptor (CAR) is a xenosensing nuclear receptor and regulator of cytochrome P450s (CYPs). However, the role of CAR as a basal regulator of CYP expression nor its role in sexually dimorphic responses have been thoroughly studied. We investigated basal regulation and sexua...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798732/ https://ncbi.nlm.nih.gov/pubmed/19041682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2008.11.002 |
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