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CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production
Immunity to infections relies on clonal expansion of CD8(+) T cells, their maintenance as effector CTLs, and their selection into a memory population. These processes rely on delivery of survival signals to activated CD8(+) T cells. We here reveal the mechanism by which costimulatory CD27-CD70 inter...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798690/ https://ncbi.nlm.nih.gov/pubmed/19955658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40178 |
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