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Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure
Although supraphysiological concentrations of urea are known to increase oxidative stress in cultured cells, it is generally thought that the elevated levels of urea in chronic renal failure patients have negligible toxicity. We previously demonstrated that ROS increase intracellular protein modific...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798674/ https://ncbi.nlm.nih.gov/pubmed/19955654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37672 |
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