Urea-induced ROS cause endothelial dysfunction in chronic renal failure

OBJECTIVE: The pathogenic events responsible for accelerated atherosclerosis in patients with chronic renal failure (CRF) are poorly understood. Here we investigate the hypothesis that concentrations of urea associated with CRF and increased ROS production in adipocytes might also increase ROS produ...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: D'Apolito, Maria, Du, Xueliang, Pisanelli, Daniela, Pettoello-Mantovani, Massimo, Campanozzi, Angelo, Giacco, Ferdinando, Maffione, Angela Bruna, Colia, Anna Laura, Brownlee, Michael, Giardino, Ida
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361277/
https://ncbi.nlm.nih.gov/pubmed/25682038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.01.034
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