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Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers
We focus on unique roles of miR-200c in breast, ovarian, and endometrial cancers. Members of the miR-200 family target ZEB1, a transcription factor which represses E-cadherin and other genes involved in polarity. We demonstrate that the double negative feedback loop between miR-200c and ZEB1 is func...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi Publishing Corporation
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798671/ https://ncbi.nlm.nih.gov/pubmed/20049172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/821717 |
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