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Restoration of miR-200c to ovarian cancer reduces tumor burden and increases sensitivity to paclitaxel

A therapeutic intervention that could decrease tumor burden and increase sensitivity to chemotherapy would have a significant impact on the high morbidity rate associated with ovarian cancer. MicroRNAs (miRNAs) have emerged as potential therapeutic candidates due to their ability to down regulate mu...

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Detalhes bibliográficos
Main Authors: Cittelly, Diana M., Dimitrova, Irina, Howe, Erin N., Cochrane, Dawn R., Jean, Annie, Spoelstra, Nicole S., Post, Miriam D., Lu, Xian, Broaddus, Russell R., Spillman, Monique A., Richer, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519949/
https://ncbi.nlm.nih.gov/pubmed/23074172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0463
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