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MicroRNA-200c Mitigates Invasiveness and Restores Sensitivity to Microtubule-Targeting Chemotherapeutic Agents

The transcription factor ZEB1 is normally not expressed in epithelial cells. When inappropriately expressed in carcinomas, ZEB1 initiates epithelial to mesenchymal transition due to its ability to repress E-cadherin and other genes involved in polarity. Recently, ZEB1 and ZEB2 have been identified a...

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Détails bibliographiques
Publié dans:Mol Cancer Ther
Auteurs principaux: Cochrane, Dawn R., Spoelstra, Nicole S., Howe, Erin N., Nordeen, Steven K., Richer, Jennifer K.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573391/
https://ncbi.nlm.nih.gov/pubmed/19435871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-1046
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