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Targets of miR-200c mediate suppression of cell motility and anoikis resistance

INTRODUCTION: miR-200c and other members of the miR-200 family promote epithelial identity by directly targeting ZEB1 and ZEB2, which repress E-cadherin and other genes involved in polarity. Loss of miR-200c is often observed in carcinoma cells that have undergone epithelial to mesenchymal transitio...

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Detalhes bibliográficos
Main Authors: Howe, Erin N, Cochrane, Dawn R, Richer, Jennifer K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219208/
https://ncbi.nlm.nih.gov/pubmed/21501518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2867
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