ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

The t(8;21) translocation between two genes known as AML1 and ETO is seen in approximately 12–15% of all acute myeloid leukemia (AML) and is the second-most-frequently observed nonrandom genetic alteration associated with AML. AML1 up-regulates a number of target genes critical to normal hematopoies...

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書目詳細資料

發表在:	Proc Natl Acad Sci U S A
Principais autores:	Wang, Jianxiang, Hoshino, Taizo, Redner, Robert L., Kajigaya, Sachiko, Liu, Johnson M.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1998
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27986/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9724795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.18.10860
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