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Oligomerization of ETO Is Obligatory for Corepressor Interaction
Nearly 40% of cases of acute myelogenous leukemia (AML) of the M2 subtype are due to a chromosomal translocation that combines a sequence-specific DNA binding protein, AML1, with a potent transcriptional repressor, ETO. ETO interacts with nuclear receptor corepressors SMRT and N-CoR, which recruit h...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC88789/ https://ncbi.nlm.nih.gov/pubmed/11113190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.1.156-163.2001 |
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