Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7

Abstract The 2525 amino acid SMRT corepressor is an intrinsically disordered hub protein responsible for binding and coordinating the activities of multiple transcription factors and chromatin modifying enzymes. Here we have studied its interaction with HDAC7, a class IIa deacetylase that interacts...

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Hlavní autoři:	Danielle C. Desravines, Itziar Serna Martin, Robert Schneider, Philippe J. Mas, Nataliia Aleksandrova, Malene Ringkjøbing Jensen, Martin Blackledge, Darren J. Hart
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2017-06-01
Edice:	Scientific Reports
On-line přístup:	https://doi.org/10.1038/s41598-017-03718-5
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