Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7
Abstract The 2525 amino acid SMRT corepressor is an intrinsically disordered hub protein responsible for binding and coordinating the activities of multiple transcription factors and chromatin modifying enzymes. Here we have studied its interaction with HDAC7, a class IIa deacetylase that interacts...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2017-06-01
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| Serier: | Scientific Reports |
| Online adgang: | https://doi.org/10.1038/s41598-017-03718-5 |
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