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Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7

Abstract The 2525 amino acid SMRT corepressor is an intrinsically disordered hub protein responsible for binding and coordinating the activities of multiple transcription factors and chromatin modifying enzymes. Here we have studied its interaction with HDAC7, a class IIa deacetylase that interacts...

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Bibliografiset tiedot
Päätekijät: Danielle C. Desravines, Itziar Serna Martin, Robert Schneider, Philippe J. Mas, Nataliia Aleksandrova, Malene Ringkjøbing Jensen, Martin Blackledge, Darren J. Hart
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2017-06-01
Sarja:Scientific Reports
Linkit:https://doi.org/10.1038/s41598-017-03718-5
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