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Pharmacokinetics and Safety of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor, in Healthy Volunteers

S/GSK1349572 is a novel integrase inhibitor with potent in vitro anti-HIV activity, an in vitro resistance profile different from those of other integrase inhibitors, and favorable preclinical safety and pharmacokinetics (PK). Randomized, double-blind, placebo-controlled single-dose and multiple-dos...

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Bibliografiske detaljer
Main Authors: Min, Sherene, Song, Ivy, Borland, Julie, Chen, Shuguang, Lou, Yu, Fujiwara, Tamio, Piscitelli, Stephen C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798521/
https://ncbi.nlm.nih.gov/pubmed/19884365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00842-09
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