Safety and Pharmacokinetics of GSK364735, a Human Immunodeficiency Virus Type 1 Integrase Inhibitor, following Single and Repeated Administration in Healthy Adult Subjects

GSK364735 is a human immunodeficiency virus (HIV) integrase strand transfer inhibitor with potent in vitro antiviral activity. This study was a double-blind, randomized, placebo-controlled, dose escalation, phase I study to assess single- and repeated-dose safety, tolerability, pharmacokinetics (PK)...

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Detalhes bibliográficos
Main Authors: Reddy, Y. Sunila, Min, Sherene S., Borland, Julie, Song, Ivy, Lin, Jiang, Palleja, Sandra, Symonds, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167967/
https://ncbi.nlm.nih.gov/pubmed/17923489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00716-07
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