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Inducible APOBEC3G-Vif Double Stable Cell Line as a High-Throughput Screening Platform To Identify Antiviral Compounds

Inhibition of the interaction of the human cytidine-deaminase APOBEC3G (A3G) with the human immunodeficiency virus (HIV) type 1-specific viral infectivity factor (Vif) represents a novel therapeutic approach in which a cellular factor with potent antiviral activity (A3G) plays a key role. In HIV-inf...

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Detalhes bibliográficos
Main Authors: Nowotny, Boris, Schneider, Thomas, Pradel, Gabriele, Schirmeister, Tanja, Rethwilm, Axel, Kirschner, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798503/
https://ncbi.nlm.nih.gov/pubmed/19841153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00775-09
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