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Generation of Stable Cell Lines Expressing Lamivudine-Resistant Hepatitis B Virus for Antiviral-Compound Screening
Lamivudine [β-l-(−)-2′,3′-dideoxy-3′-thiacytidine] is a potent inhibitor of hepadnavirus replication and is used both to treat chronic hepatitis B virus (HBV) infections and to prevent reinfection of transplanted livers. Unfortunately, lamivudine-resistant HBV variants do arise during prolonged ther...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155849/ https://ncbi.nlm.nih.gov/pubmed/12760870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.6.1936-1942.2003 |
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