MKRN1 Induces Degradation of West Nile Virus Capsid Protein by Functioning as an E3 Ligase

West Nile virus capsid protein (WNVCp) displays pathogenic toxicity via the apoptotic pathway. However, a cellular mechanism protective against this toxic effect has not been observed so far. Here, we identified Makorin ring finger protein 1 (MKRN1) as a novel E3 ubiquitin ligase for WNVCp. The cyto...

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Sonraí Bibleagrafaíochta
Main Authors: Ko, Aram, Lee, Eun-Woo, Yeh, Jung-Yong, Yang, Mi-Ran, Oh, Wonkyung, Moon, Jin-San, Song, Jaewhan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Virus-Cell Interactions
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798448/
https://ncbi.nlm.nih.gov/pubmed/19846531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00725-09
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