Porcine MKRN1 Modulates the Replication and Pathogenesis of Porcine Circovirus Type 2 by Inducing Capsid Protein Ubiquitination and Degradation

Porcine circovirus type 2 (PCV2) capsid protein (Cap) is a unique structure protein that plays pivotal roles in the process of viral replication and pathogenesis. Herein, we characterized a putative porcine Makorin RING finger protein 1 (pMKRN1) variant, an N-terminal-truncated variant of putative f...

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Vydáno v:J Virol
Hlavní autoři: Wang, Tongtong, Du, Qian, Wu, Xingchen, Niu, Yingying, Guan, Lijuan, Wang, Zhenyu, Zhao, Xiaomin, Liu, Shan-Lu, Tong, Dewen, Huang, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952126/
https://ncbi.nlm.nih.gov/pubmed/29514908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00100-18
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