West Nile virus capsid protein induces p53‐mediated apoptosis via the sequestration of HDM2 to the nucleolus

The capsid protein of the West Nile virus (WNV) functions as an apoptotic agonist via the induction of mitochondrial dysfunction and the activation of caspases‐9 and ‐3. Here, we have determined that the WNV capsid (WNVCp) is capable of binding to and sequestering HDM2 into the nucleolus. WNVCp was...

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Dettagli Bibliografici
Pubblicato in:Cell Microbiol
Autori principali: Yang, Mi‐Ran, Lee, Sung Ryul, Oh, Wonkyung, Lee, Eun‐Woo, Yeh, Jung‐Yong, Nah, Jin‐Ju, Joo, Yi‐Seok, Shin, Jaekyoon, Lee, Han‐Woong, Pyo, Suhkneung, Song, Jaewhan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2007
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162166/
https://ncbi.nlm.nih.gov/pubmed/17697133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2007.01027.x
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