Enhanced PD-1 Expression by T Cells in Cerebrospinal Fluid Does Not Reflect Functional Exhaustion during Chronic Human Immunodeficiency Virus Type 1 Infection

During chronic viral infections, T cells are exhausted due to constant antigen exposure and are associated with enhanced programmed death 1 (PD-1) expression. Deficiencies in the PD-1/programmed death-ligand 1 (PD-L1) pathway are associated with autoimmune diseases, including those of the central ne...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sadagopal, Shanmugalakshmi, Lorey, Shelly L., Barnett, Louise, Sutherland, Deborah, Basham, Rebecca, Erdem, Husamettin, Kalams, Spyros A., Haas, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798447/
https://ncbi.nlm.nih.gov/pubmed/19828602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01181-09
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados